The discussion on drugs and its effects is extensive. However, there is a line within that discussion which focuses on certain drugs and whether they induce spiritual effects. In order to start on such a topic it is of upmost importance to discuss and set the basis of the discussion; that being the methodology and the terms which will be used. The definition for ‘mysticism’ and ‘mystical experience’ is riddled with multiplicities and has been a colourful tug of war between scholars and mystics themselves. Focusing on the question, the definition of a ‘mystical experience’ is somewhat much more difficult to define as it is a personal esoteric experience. If we were to personify a mystical experience it would be an introvert who lives within themselves and stutters when being made to make small talk. A mystical experience is not just silent or vague like an introvert would be accused of. Inside there is substance, a science and a serious thinker. For the sake of this misunderstanding, I aim to clearly lay out what my definitions are and how I intend to use them against the discussion of the effect of drugs.